Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 7/20 | 0.66 |
| ▸ | NAAA | Q02083 | 1/20 | 0.58 |
| ▸ | HRH2 | P25021 | 1/20 | 0.53 |
| ▸ | HRH1 | P35367 | 1/20 | 0.53 |
| ▸ | HTR7 | P34969 | 1/20 | 0.53 |
| ▸ | STS | P08842 | 4/20 | 0.53 |
| ▸ | FAAH | O00519 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9440245 | 1.00 | HSD17B3 (0.66) | HSD17B3NAAAHRH2HRH1HTR7 | |
| SCHEMBL9146061 | 1.00 | HSD17B3 (0.66) | HSD17B3NAAAHRH2HRH1HTR7 | |
| SCHEMBL29959715 | 1.00 | HSD17B3 (0.66) | HSD17B3NAAAHRH2HRH1HTR7 | |
| SCHEMBL3983005 | 0.98 | HSD17B3 (0.65) | HSD17B3NAAAHRH2HRH1HTR7 | |
| SCHEMBL7220547 | 0.92 | HSD17B3 (0.63) | HSD17B3NAAAHRH2HRH1HTR7 | |
| SCHEMBL13085847 | 0.86 | HSD17B3 (0.85) | HSD17B3HTR7STSL3MBTL1LMNA | |
| SCHEMBL13085794 | 0.86 | HSD17B3 (0.85) | HSD17B3HTR7STSL3MBTL1LMNA | |
| Propyl 4-Pyridyl Ketone SCHEMBL4952700 | 0.84 | HSD17B3 (0.61) | HSD17B3NAAAHTR7STSL3MBTL1 | |
| SCHEMBL18753070 | 0.84 | HSD17B3 (0.84) | HSD17B3HTR7STSL3MBTL1LMNA | |
| SCHEMBL964590 | 0.81 | L3MBTL1 (0.80) | HSD17B3L3MBTL1LMNAMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0046446-A1 | Polyazaheterocyclic compounds, process for their preparation and pharmaceutical compositions containing them | CIBA-GEIGY AG (CH) | 1982-02-24 | — | — | EP | disclosed |