Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | TERT | O14746 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11262480 | 0.82 | HTR2C (0.40) | NPC1RAB9ATSHRLMNAMAPK1 | |
| Hydrochloric Acid SCHEMBL11254022 | 0.81 | RAD52 (0.41) | NPC1RAB9ATSHRLMNAMAPK1 | |
| SCHEMBL11265320 | 0.80 | HTR2C (0.41) | DRD2NPC1RAB9ATSHRLMNA | |
| SCHEMBL11260549 | 0.75 | HTR2C (0.36) | NPC1RAB9ATSHRLMNAMAPK1 | |
| SCHEMBL11257441 | 0.70 | HTR2C (0.39) | DRD2NPC1RAB9AHDAC6ALDH1A1 | |
| SCHEMBL11265935 | 0.70 | KDM4E (0.64) | TSHRKDM4EPIK3CAALDH1A1KMT2A | |
| SCHEMBL11262482 | 0.70 | KDM4E (0.64) | TSHRKDM4EPIK3CAALDH1A1KMT2A | |
| SCHEMBL11265827 | 0.70 | HTR2C (0.39) | DRD2NPC1RAB9ATSHRHDAC6 | |
| SCHEMBL11258507 | 0.70 | SMN1; SMN2 (0.39) | NPC1RAB9ATSHRLMNAKDM4E | |
| SCHEMBL11260544 | 0.69 | HTT (0.42) | NPC1RAB9ATSHRLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344946-A | ANTIARTHRITICS, ANTIRHEUMATICS | BOEHRINGER INGELHEIM GMBH (DE) | 1982-08-17 | — | — | US | disclosed |