SCHEMBL1126777

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1126837	0.85	BRD4 (0.37)	HSD17B10TSHRBRD4KDM4EGFER
	SCHEMBL1127167	0.85	BRD4 (0.37)	HSD17B10MAPK1BRD4KDM4ERAB9A
	SCHEMBL1127225	0.76	CCNC (0.41)	HSD17B10MAPK1BRD4KDM4ERAB9A
	SCHEMBL1126922	0.74	MAPT (0.43)	HSD17B10MAPK1TSHRKDM4ERAB9A
	SCHEMBL1988726	0.72	CCNC (0.40)	HSD17B10MAPK1BRD4KDM4ERAB9A
	SCHEMBL16588812	0.72	CCNC (0.38)	HSD17B10MAPK1BRD4KDM4ERAB9A
	SCHEMBL1127170	0.70	CNR1 (0.43)	MAPK1TSHRBRD4RAB9AALDH1A1
	SCHEMBL1990116	0.68	BRD4 (0.46)	HSD17B10BRD4KDM4EALDH1A1HPGD
	SCHEMBL1127035	0.67	BRD4 (0.45)	BRD4KDM4EALDH1A1HPGDCNR1
	SCHEMBL1988099	0.66	BRD4 (0.37)	HSD17B10BRD4KDM4ERAB9AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.