Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | KMO | O15229 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 2/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11274649 | 0.84 | KMO (0.49) | TSHRL3MBTL1ALDH1A1MAPTHPGD | |
| SCHEMBL28744433 | 0.80 | TSHR (0.52) | TSHRL3MBTL1ALDH1A1MAPTHPGD | |
| SCHEMBL11484881 | 0.76 | TSHR (0.55) | TSHRL3MBTL1ALDH1A1MAPTHPGD | |
| SCHEMBL2598225 | 0.76 | TSHR (0.59) | TSHRL3MBTL1ALDH1A1MAPTHPGD | |
| SCHEMBL11765691 | 0.75 | TSHR (0.53) | TSHRL3MBTL1ALDH1A1MAPTHPGD | |
| SCHEMBL11219161 | 0.74 | TSHR (0.49) | TSHRL3MBTL1ALDH1A1MAPTHPGD | |
| SCHEMBL10956733 | 0.74 | KMT2A (0.49) | TSHRL3MBTL1ALDH1A1MAPTHPGD | |
| SCHEMBL5194237 | 0.73 | TSHR (0.55) | TSHRL3MBTL1ALDH1A1MAPTHPGD | |
| SCHEMBL5197853 | 0.72 | TSHR (0.59) | TSHRL3MBTL1ALDH1A1MAPTHPGD | |
| Hydrochloric Acid SCHEMBL9537072 | 0.72 | TSHR (0.46) | TSHRL3MBTL1ALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344957-A | Benz-acyl-benzimidazole derivatives and antiallergic compositions | CIBA-GEIGY CORPORATION (US) | 1982-08-17 | — | — | US | disclosed |
| US-4213993-A | ANTIALLERGENS | CIBA-GEIGY CORPORATION (US) | 1980-07-22 | — | — | US | disclosed |
| US-4141982-A | ANTIALLERGENS | CIBA-GEIGY CORPORATION (US) | 1979-02-27 | — | — | US | disclosed |