Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2983914 | 0.73 | LMNA (0.39) | CYP2C19LMNA | |
| SCHEMBL818254 | 0.73 | LMNA (0.39) | CYP2C19LMNA | |
| SCHEMBL5514558 | 0.68 | — | — | |
| SCHEMBL12215996 | 0.68 | — | — | |
| SCHEMBL4826203 | 0.68 | — | — | |
| SCHEMBL2978531 | 0.67 | SMN1; SMN2 (0.41) | CYP2C19LMNA | |
| SCHEMBL7620707 | 0.67 | LMNA (0.38) | CYP2C19LMNA | |
| SCHEMBL6473670 | 0.67 | LMNA (0.38) | CYP2C19LMNA | |
| SCHEMBL16612748 | 0.67 | HCAR2 (0.32) | — | |
| SCHEMBL16612747 | 0.67 | HCAR2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0009539-B1 | FLUORINATED POLYENES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1982-12-22 | — | — | EP | disclosed |
| US-4299995-A | ANTITUMOR AGENTS AND TREATMENT OF SKIN DISORDERS | HOFFMANN-LA ROCHE INC. (US) | 1981-11-10 | — | — | US | disclosed |
| US-4231944-A | 9-FURYL SUBSTITUTED, 4- OR 6-FLUORO DERIVATIVES OF RETINOIC ACID, ANTITUMOR AGENTS, TREATMENT OF ACNE | HOFFMANN-LA ROCHE INC. (US) | 1980-11-04 | — | — | US | disclosed |
| EP-0009539-A1 | Fluorinated polyenes, their preparation and pharmaceutical compositions containing them | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1980-04-16 | — | — | EP | disclosed |
| US-4171318-A | 9-(SUBSTITUTED PHENYL), 4 OR 6-FLUORO-RETINOIC ACID DERIVATIVES, ANTITUMOR AND ANTIACNE AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1979-10-16 | — | — | US | disclosed |