Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 6/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.40 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11279295 | 0.80 | HTT (0.71) | HTTSMN1; SMN2MAPTLMNAKMT2A | |
| SCHEMBL11275070 | 0.80 | HTT (0.71) | HTTSMN1; SMN2MAPTLMNAKMT2A | |
| SCHEMBL11280402 | 0.80 | HTT (0.61) | HTTSMN1; SMN2MAPTLMNAKMT2A | |
| SCHEMBL11271461 | 0.79 | HTT (0.47) | HTTSMN1; SMN2MAPTLMNAKMT2A | |
| SCHEMBL11273330 | 0.78 | GLP1R (0.38) | HTTSMN1; SMN2LMNAADORA3ADORA1 | |
| SCHEMBL11152827 | 0.76 | HTT (0.39) | HTTSMN1; SMN2MAPTLMNAKMT2A | |
| SCHEMBL11277571 | 0.75 | HTT (0.51) | HTTSMN1; SMN2MAPTLMNAKMT2A | |
| SCHEMBL27767382 | 0.74 | HTT (0.76) | HTTSMN1; SMN2MAPTLMNAKMT2A | |
| SCHEMBL11263264 | 0.71 | HTT (0.75) | HTTSMN1; SMN2MAPTLMNAKMT2A | |
| SCHEMBL11276109 | 0.69 | HTT (0.71) | HTTSMN1; SMN2MAPTLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0018493-B1 | 2-SULFONYL-QUINOXALINES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS MICROBICIDES | BAYER AG (DE) | 1982-12-01 | — | — | EP | disclosed |
| EP-0018493-A1 | 2-Sulfonyl-quinoxalines, processes for their preparation and their use as microbicides | BAYER AG (DE) | 1980-11-12 | — | — | EP | disclosed |