Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 6/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11271461 | 0.85 | HTT (0.47) | HTTSMN1; SMN2MAPTLMNAFFAR2 | |
| SCHEMBL11268415 | 0.75 | HTT (0.56) | HTTSMN1; SMN2MAPTLMNAFFAR2 | |
| SCHEMBL11280402 | 0.73 | HTT (0.61) | HTTSMN1; SMN2MAPTLMNAFFAR2 | |
| SCHEMBL11370935 | 0.73 | HTT (0.49) | HTTSMN1; SMN2MAPTLMNAFFAR2 | |
| SCHEMBL27767382 | 0.73 | HTT (0.76) | HTTSMN1; SMN2MAPTLMNAPKM | |
| SCHEMBL27975420 | 0.71 | HTT (0.47) | HTTSMN1; SMN2MAPTLMNAPKM | |
| SCHEMBL11275070 | 0.71 | HTT (0.71) | HTTSMN1; SMN2MAPTLMNAFFAR2 | |
| SCHEMBL11279295 | 0.71 | HTT (0.71) | HTTSMN1; SMN2MAPTLMNAFFAR2 | |
| SCHEMBL21782512 | 0.70 | HTT (0.38) | HTTSMN1; SMN2MAPTLMNAPKM | |
| SCHEMBL3377180 | 0.69 | PKM (0.59) | HTTSMN1; SMN2LMNAFFAR2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0018493-B1 | 2-SULFONYL-QUINOXALINES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS MICROBICIDES | BAYER AG (DE) | 1982-12-01 | — | — | EP | disclosed |