Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 2/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | PORCN | Q9H237 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1126575 | 0.86 | MCHR1 (0.36) | KCNA5TDP1KMT2AMEN1NPC1 | |
| SCHEMBL1991373 | 0.84 | HCRTR1 (0.39) | HCRTR1HCRTR2KCNA5SMN1; SMN2TDP1 | |
| SCHEMBL1644580 | 0.82 | MAPT (0.37) | HCRTR1HCRTR2KCNA5SMN1; SMN2TDP1 | |
| SCHEMBL2231282 | 0.81 | SMN1; SMN2 (0.41) | HCRTR1HCRTR2KCNA5SMN1; SMN2TDP1 | |
| SCHEMBL1990047 | 0.80 | HCRTR1 (0.38) | HCRTR1HCRTR2KCNA5SMN1; SMN2TDP1 | |
| SCHEMBL1646398 | 0.80 | SMN1; SMN2 (0.51) | HCRTR1HCRTR2SMN1; SMN2TDP1KMT2A | |
| SCHEMBL1646743 | 0.79 | LMNA (0.40) | HCRTR1HCRTR2KCNA5SMN1; SMN2KMT2A | |
| SCHEMBL1646859 | 0.79 | SMN1; SMN2 (0.38) | HCRTR1HCRTR2KCNA5SMN1; SMN2TDP1 | |
| SCHEMBL2231172 | 0.79 | LMNA (0.43) | HCRTR1HCRTR2SMN1; SMN2TDP1TP53 | |
| SCHEMBL2233127 | 0.79 | LMNA (0.40) | HCRTR1HCRTR2KCNA5SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283006-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G Limited (GB) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009130481-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2009-10-29 | — | — | WO | disclosed |