Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 7/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1126845 | 0.86 | HCRTR1 (0.41) | MEN1KMT2AALDH1A1NPC1DGAT1 | |
| SCHEMBL1988542 | 0.85 | RIPK2 (0.38) | MCHR1MEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL1645861 | 0.84 | ALDH1A1 (0.35) | MCHR1MEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL1646663 | 0.82 | LMNA (0.42) | MCHR1MEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL1646520 | 0.82 | SMN1; SMN2 (0.50) | MCHR1MEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL1990441 | 0.82 | DGAT1 (0.38) | MCHR1MEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL1645695 | 0.81 | LMNA (0.42) | MCHR1MEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL1646317 | 0.81 | LMNA (0.41) | MCHR1MEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL1647758 | 0.81 | LMNA (0.39) | MCHR1MEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL1646759 | 0.80 | LMNA (0.40) | MCHR1MEN1KMT2AALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283006-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G Limited (GB) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009130481-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2009-10-29 | — | — | WO | disclosed |