SCHEMBL11268469

SCHEMBL11268469

O=C(Cl)ON1CCNC1=O

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.36
POLB P06746 2/20 0.36
NPSR1 Q6W5P4 1/20 0.33
GAA P10253 1/20 0.33
FAAH O00519 1/20 0.32
NAAA Q02083 1/20 0.32
CRHBP P24387 1/20 0.31
CRHR2 Q13324 1/20 0.31
HSD17B10 Q99714 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18116959 0.79 NPSR1 (0.37) ALDH1A1POLBNPSR1GAAFAAH
SCHEMBL6308981 0.75 FAAH (0.39) ALDH1A1POLBNPSR1GAAFAAH
SCHEMBL17978959 0.75 ALDH1A1 (0.39) ALDH1A1POLBNPSR1GAAMAPT
SCHEMBL11637410 0.73
SCHEMBL5167031 0.73 ALDH1A1 (0.34) ALDH1A1NPSR1FAAHNAAAHSD17B10
SCHEMBL17978980 0.73 ALDH1A1 (0.42) ALDH1A1POLBNPSR1GAAMAPT
SCHEMBL27843517 0.72 ALDH1A1 (0.32) ALDH1A1POLBNPSR1GAA
SCHEMBL28705890 0.72 NPSR1 (0.33) NPSR1FAAHNAAAHSD17B10MAPT
SCHEMBL9168611 0.72 TSHR (0.42) ALDH1A1POLBFAAHNAAAHSD17B10
SCHEMBL28695499 0.71 KLK5 (0.35) POLBNPSR1GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0054514-A1 Derivatives of aminopapulacandin having antibiotic activity CIBA-GEIGY AG (CH) 1982-06-23 EP disclosed