Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK1 | P49759 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11252940 | 0.94 | CLK1 (0.56) | CLK1ALDH1A1KDM4EHTTSMN1; SMN2 | |
| SCHEMBL11257442 | 0.83 | ALDH1A1 (0.71) | CLK1ALDH1A1KDM4EHTTSMN1; SMN2 | |
| SCHEMBL11265331 | 0.82 | KDM4E (0.62) | CLK1ALDH1A1KDM4EHTTSMN1; SMN2 | |
| SCHEMBL11262482 | 0.81 | KDM4E (0.64) | CLK1ALDH1A1KDM4EHTTSMN1; SMN2 | |
| SCHEMBL11265935 | 0.81 | KDM4E (0.64) | CLK1ALDH1A1KDM4EHTTSMN1; SMN2 | |
| SCHEMBL11255872 | 0.80 | CLK1 (0.58) | CLK1ALDH1A1KDM4EHTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11254026 | 0.80 | KDM4E (0.63) | CLK1ALDH1A1KDM4EHTTSMN1; SMN2 | |
| SCHEMBL11265830 | 0.80 | CLK1 (0.58) | CLK1ALDH1A1KDM4EHTTSMN1; SMN2 | |
| SCHEMBL11256985 | 0.79 | CLK1 (0.57) | CLK1ALDH1A1HTTSMN1; SMN2POLB | |
| SCHEMBL11254906 | 0.79 | ALDH1A1 (0.75) | CLK1ALDH1A1HTTSMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344946-A | ANTIARTHRITICS, ANTIRHEUMATICS | BOEHRINGER INGELHEIM GMBH (DE) | 1982-08-17 | — | — | US | disclosed |