Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK1 | P49759 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11268499 | 0.94 | CLK1 (0.62) | CLK1ALDH1A1KDM4EPOLBHTT | |
| SCHEMBL11256242 | 0.82 | CLK1 (0.52) | CLK1CA1CA2CA9ALDH1A1 | |
| SCHEMBL11257442 | 0.79 | ALDH1A1 (0.71) | CLK1ALDH1A1KDM4EPOLBHTT | |
| SCHEMBL11265331 | 0.77 | KDM4E (0.62) | CLK1ALDH1A1KDM4EPOLBHTT | |
| SCHEMBL11252930 | 0.77 | CLK1 (0.41) | CLK1CA1CA2CA9ALDH1A1 | |
| SCHEMBL11257686 | 0.77 | TSHR (0.48) | CLK1ALDH1A1KDM4EPOLBHTT | |
| SCHEMBL11262482 | 0.76 | KDM4E (0.64) | CLK1ALDH1A1KDM4EPOLBHTT | |
| SCHEMBL11265935 | 0.76 | KDM4E (0.64) | CLK1ALDH1A1KDM4EPOLBHTT | |
| Water SCHEMBL11255627 | 0.76 | TSHR (0.48) | CLK1ALDH1A1KDM4EPOLBHTT | |
| SCHEMBL11255872 | 0.75 | CLK1 (0.58) | CLK1ALDH1A1KDM4EPOLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344946-A | ANTIARTHRITICS, ANTIRHEUMATICS | BOEHRINGER INGELHEIM GMBH (DE) | 1982-08-17 | — | — | US | disclosed |