Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.45 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.45 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11268595 | 1.00 | KMT2A (0.45) | KMT2AMEN1KDM4EALDH1A1SAE1 | |
| SCHEMBL11281443 | 0.96 | KMT2A (0.47) | KMT2AMEN1KDM4EALDH1A1SAE1 | |
| SCHEMBL11281436 | 0.96 | KMT2A (0.47) | KMT2AMEN1KDM4EALDH1A1SAE1 | |
| SCHEMBL11273090 | 0.88 | MGLL (0.50) | KMT2AMEN1ALDH1A1MGLLMAPT | |
| SCHEMBL11277245 | 0.87 | MGLL (0.48) | KMT2AMEN1ALDH1A1MGLLMAPT | |
| SCHEMBL11272864 | 0.85 | KMT2A (0.46) | KMT2AMEN1KDM4EALDH1A1NTSR1 | |
| SCHEMBL11272853 | 0.85 | KMT2A (0.46) | KMT2AMEN1KDM4EALDH1A1NTSR1 | |
| SCHEMBL11267592 | 0.84 | KMT2A (0.47) | KMT2AMEN1ALDH1A1MGLLMAPT | |
| SCHEMBL11301990 | 0.84 | SAE1 (0.56) | KMT2AMEN1KDM4EALDH1A1SAE1 | |
| SCHEMBL11301991 | 0.84 | SAE1 (0.56) | KMT2AMEN1KDM4EALDH1A1SAE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4310533-A | INHIBITING PLASMIN AND-OR TRYSIN ACTIVITY | ONO PHARMACEUTICAL CO., LTD. (JP) | 1982-01-12 | — | — | US | disclosed |