Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11277245 | 0.99 | MGLL (0.48) | MGLLKMT2AHDAC1HDAC2HPGD | |
| SCHEMBL11267592 | 0.96 | KMT2A (0.47) | MGLLKMT2AHDAC1HDAC2HPGD | |
| SCHEMBL11280102 | 0.91 | KLK7 (0.46) | MGLLKMT2AHDAC1HDAC2MAPT | |
| SCHEMBL11271598 | 0.91 | KLK7 (0.46) | MGLLKMT2AHDAC1HDAC2MAPT | |
| SCHEMBL11272851 | 0.89 | MGLL (0.43) | MGLLKMT2AHDAC1HDAC2HPGD | |
| SCHEMBL11268601 | 0.88 | KMT2A (0.45) | MGLLKMT2AHPGDMAPTMEN1 | |
| SCHEMBL11268595 | 0.88 | KMT2A (0.45) | MGLLKMT2AHPGDMAPTMEN1 | |
| SCHEMBL11272855 | 0.88 | KMT2A (0.46) | MGLLKMT2AHPGDITGB3ITGA2B | |
| SCHEMBL11271175 | 0.86 | KLK7 (0.47) | KMT2AMAPTMEN1ALDH1A1NPC1 | |
| SCHEMBL11273835 | 0.85 | KMT2A (0.40) | MGLLKMT2AHDAC1HDAC2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4310533-A | INHIBITING PLASMIN AND-OR TRYSIN ACTIVITY | ONO PHARMACEUTICAL CO., LTD. (JP) | 1982-01-12 | — | — | US | disclosed |