SCHEMBL11268792

SCHEMBL11268792

O=c1cnc2occc2[nH]1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPKAPK2 P49137 1/20 0.41
RPS6KA3 P51812 1/20 0.41
CSNK2A1 P68400 1/20 0.41
PLK3 Q9H4B4 1/20 0.41
ALDH1A1 P00352 3/20 0.37
PDE3B Q13370 11/20 0.35
PDE3A Q14432 11/20 0.35
NOS1 P29475 1/20 0.31
NOS2 P35228 1/20 0.31
DAO P14920 1/20 0.31
KDM4E B2RXH2 2/20 0.30
HSD17B10 Q99714 2/20 0.30
LMNA P02545 1/20 0.30
GLA P06280 1/20 0.30
PMP22 Q01453 1/20 0.30
MEN1 O00255 1/20 0.30
MAPT P10636 1/20 0.30
THRB P10828 1/20 0.30
HPGD P15428 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5498113 0.67 MAPKAPK2 (0.47) MAPKAPK2RPS6KA3CSNK2A1PLK3ALDH1A1
SCHEMBL217336 0.66
SCHEMBL30752490 0.64 DAO (0.46) PDE3BPDE3ADAO
SCHEMBL5039773 0.63
SCHEMBL37862 0.63 ALDH1A1 (0.59) MAPKAPK2RPS6KA3CSNK2A1PLK3ALDH1A1
SCHEMBL5036878 0.63
SCHEMBL5036556 0.63
SCHEMBL29396007 0.63 ALDH1A1 (0.59) MAPKAPK2RPS6KA3CSNK2A1PLK3ALDH1A1
SCHEMBL15900200 0.62 PDE3B (0.41) MAPKAPK2RPS6KA3CSNK2A1PLK3ALDH1A1
SCHEMBL10473563 0.62 IDO1 (0.43) ALDH1A1KDM4EHSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4363664-A AQEOUS DISPERSION CONTAINING DYESTUFF PRECURSORS AND SURFACTANT STERLING DRUG INC. (US) 1982-12-14 US claimed
US-4363664-A AQEOUS DISPERSION CONTAINING DYESTUFF PRECURSORS AND SURFACTANT STERLING DRUG INC. (US) 1982-12-14 US disclosed
US-4337340-A FROM DIPHENYLAMINES AND BENZOYL OR 3-INDOLYLCARBONYL PYRIDINE- OR PYRAZINECARBOXYLIC ACIDS STERLING DRUG INC. (US) 1982-06-29 US disclosed
US-4337340-A FROM DIPHENYLAMINES AND BENZOYL OR 3-INDOLYLCARBONYL PYRIDINE- OR PYRAZINECARBOXYLIC ACIDS STERLING DRUG INC. (US) 1982-06-29 US disclosed
US-4337340-A FROM DIPHENYLAMINES AND BENZOYL OR 3-INDOLYLCARBONYL PYRIDINE- OR PYRAZINECARBOXYLIC ACIDS STERLING DRUG INC. (US) 1982-06-29 US disclosed
US-4243250-A FUROPYRIDINONES OR FUROPYRAZINONES AS COLOR FORMERS STERLING DRUG INC. (US) 1981-01-06 US disclosed
US-4243250-A FUROPYRIDINONES OR FUROPYRAZINONES AS COLOR FORMERS STERLING DRUG INC. (US) 1981-01-06 US disclosed
US-4211872-A COLOR FORMERS FREEDOM CHEMICAL COMPANY 1980-07-08 US disclosed
US-4211872-A COLOR FORMERS FREEDOM CHEMICAL COMPANY 1980-07-08 US disclosed
US-4211872-A COLOR FORMERS FREEDOM CHEMICAL COMPANY 1980-07-08 US disclosed