⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8112681 | 0.97 | CA1 (0.52) | — | |
| SCHEMBL1259911 | 0.97 | — | — | |
| SCHEMBL16155543 | 0.97 | CA1 (0.52) | — | |
| SCHEMBL1640600 | 0.93 | — | — | |
| SCHEMBL4421353 | 0.86 | — | — | |
| SCHEMBL5997632 | 0.86 | CA12 (0.44) | — | |
| SCHEMBL5844650 | 0.77 | MGLL (0.47) | — | |
| SCHEMBL1445411 | 0.75 | ALDH1A1 (0.37) | — | |
| SCHEMBL3436216 | 0.75 | CYP1A2 (0.48) | — | |
| SCHEMBL1127327 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 155 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117510413-A | DCLK1 kinase inhibitor and preparation method and application thereof | 杭州医学院 | 2024-02-06 | — | — | CN | claimed |
| US-20050090486-A1 | Trisubstituted pyrimidines | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2005-04-28 | — | — | US | claimed |
| US-20030134838-A1 | Trisubstituted pyrimidines | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2003-07-17 | — | — | US | claimed |
| US-4093415-A | DYEING, OPTICAL BRIGHTENERS, CARRIERS | CIBA GEIGY AG (CH) | 1978-06-06 | — | — | US | claimed |
| US-12378224-B2 | Heteroaryl compounds and their use as Mer inhibitors | DONG-A SOCIO HOLDINGS CO., LTD. (KR) | 2025-08-05 | — | — | US | disclosed |
| WO-2025151402-A1 | THIAZOLE TRPML1 AGONISTS AND USES THEREOF | LIBRA THERAPEUTICS, INC. (US) | 2025-07-17 | — | — | WO | disclosed |
| CN-116041606-B | Fluorine-containing acrylate polymer adhesive and preparation method and application thereof | 东华大学 | 2024-02-27 | — | — | CN | disclosed |
| CN-117510413-A | DCLK1 kinase inhibitor and preparation method and application thereof | 杭州医学院 | 2024-02-06 | — | — | CN | disclosed |
| CN-116041606-A | Fluorine-containing acrylate polymer adhesive and preparation method and application thereof | 东华大学 | 2023-05-02 | — | — | CN | disclosed |
| US-11168080-B2 | Dynamin-1-like protein inhibitors | MITOBRIDGE, INC. (US) | 2021-11-09 | — | — | US | disclosed |
| US-11168080-B2 | Dynamin-1-like protein inhibitors | MITOBRIDGE, INC. (US) | 2021-11-09 | — | — | US | disclosed |
| US-20200131172-A1 | DYNAMIN-1-LIKE PROTEIN INHIBITORS | Astellas Engineered Small Molecules US, Incorporated | 2020-04-30 | — | — | US | disclosed |
| EP-0674513-A1 | RETROVIRAL PROTEASE INHIBITING COMPOUNDS. | ABBOTT LAB (US) | 1995-10-04 | — | — | EP | disclosed |
| US-5455351-A | Treating HIV or AIDS | ABBOTT LABORATORIES (US) | 1995-10-03 | — | — | US | disclosed |
| EP-0683772-A4 | RETROVIRAL PROTEASE INHIBITING COMPOUNDS. | ABBOTT LAB (US) | 1995-09-27 | — | — | EP | disclosed |
| WO-1994019332-A1 | RETROVIRAL PROTEASE INHIBITING COMPOUNDS | ABBOTT LABORATORIES (US) | 1994-09-01 | — | — | WO | disclosed |
| WO-1994014436-A1 | RETROVIRAL PROTEASE INHIBITING COMPOUNDS | ABBOTT LABORATORIES (US) | 1994-07-07 | — | — | WO | disclosed |
| US-4275014-A | SULFUR VULCANIZABLE RUBBERS | PENNWALT CORPORATION (US) | 1981-06-23 | — | — | US | disclosed |
| US-4220589-A | N-(Oxazolidinothio) imides that provide scorch retardant nonblooming elastomeric compositions | PENNWALT CORPORATION (US) | 1980-09-02 | — | — | US | disclosed |
| US-4093415-A | DYEING, OPTICAL BRIGHTENERS, CARRIERS | CIBA GEIGY AG (CH) | 1978-06-06 | — | — | US | disclosed |