Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | PGR | P06401 | 2/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | AR | P10275 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.44 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.44 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.44 |
| ▸ | GSTA1 | P08263 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL11500463 | 0.87 | HPGD (0.48) | HPGDLMNACYP1A2PGRSLC6A2 | |
| SCHEMBL10664252 | 0.85 | MAPK13 (0.43) | HPGDLMNAALOX15MAPK13MAPK12 | |
| SCHEMBL11434121 | 0.81 | MAPK13 (0.48) | LMNAMAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL11400442 | 0.81 | CYP3A4 (0.42) | HPGDLMNACYP1A2PGRSLC6A2 | |
| SCHEMBL11419596 | 0.80 | MAPT (0.49) | HPGDLMNACYP1A2PGRSLC6A2 | |
| SCHEMBL11455560 | 0.79 | SMN1; SMN2 (0.52) | PPARGPPARAALDH1A1RAB9ANPC1 | |
| SCHEMBL10949791 | 0.76 | CYP2C9 (0.45) | HPGDLMNAALOX15PPARGPPARA | |
| SCHEMBL1090803 | 0.74 | PPARG (0.55) | LMNAPPARGPPARAALDH1A1KDM4E | |
| SCHEMBL10659219 | 0.74 | PPARG (0.39) | HPGDLMNAALOX15MAPK13MAPK12 | |
| SCHEMBL2924890 | 0.72 | CES2 (0.58) | HPGDLMNACYP1A2PGRSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4323691-A | Hydroxyaminomethyl derivatives of benzoyl di-substituted α-phenoxyalkanoyl esters | ABBOTT LABORATORIES (US) | 1982-04-06 | — | — | US | disclosed |
| US-4220801-A | Process for making 4-aroyl-substituted phenoxyacetic acids | ABBOTT LABORATORIES (US) | 1980-09-02 | — | — | US | disclosed |
| US-4220801-A | Process for making 4-aroyl-substituted phenoxyacetic acids | ABBOTT LABORATORIES (US) | 1980-09-02 | — | — | US | disclosed |