Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.58 |
| ▸ | CES1 | P23141 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | LIG1 | P18858 | 1/20 | 0.53 |
| ▸ | GSTA1 | P08263 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.52 |
| ▸ | CA4 | P22748 | 1/20 | 0.52 |
| ▸ | CA6 | P23280 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29399311 | 0.89 | CES2 (0.71) | CES2CES1ALDH1A1RECQLHPGD | |
| SCHEMBL50416 | 0.89 | CES2 (0.71) | CES2CES1ALDH1A1RECQLHPGD | |
| SCHEMBL3444846 | 0.86 | CES2 (0.68) | CES2CES1ALDH1A1RECQLHPGD | |
| 2,2'-Dihydroxybenzphenone SCHEMBL29572496 | 0.86 | HPGD (0.67) | ALDH1A1RECQLLIG1GSTA1KDM4E | |
| 2,2'-Dihydroxybenzphenone SCHEMBL18422 | 0.86 | HPGD (0.67) | ALDH1A1RECQLLIG1GSTA1KDM4E | |
| SCHEMBL10610938 | 0.85 | LIG1 (0.62) | CES2CES1ALDH1A1LIG1GSTA1 | |
| 2,2'-Dihydroxybenzphenone SCHEMBL11145317 | 0.84 | LIG1 (0.64) | ALDH1A1RECQLLIG1GSTA1KDM4E | |
| 2,2'-Dihydroxybenzphenone SCHEMBL6652370 | 0.84 | LIG1 (0.64) | ALDH1A1RECQLLIG1GSTA1KDM4E | |
| SCHEMBL455832 | 0.84 | LIG1 (0.64) | ALDH1A1RECQLLIG1GSTA1KDM4E | |
| SCHEMBL9833888 | 0.83 | G6PD (0.56) | CES2CES1ALDH1A1RECQLKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994005276-A1 | CYTOTOXIC COMPOUNDS | MORGAN LEE R (US) | 1994-03-17 | — | — | WO | claimed |
| EP-1486193-B1 | METHOD OF STABILIZING SILICONE OIL-CONTAINING COSMETIC COMPOSITION | HAKUTO KK (JP) | 2010-09-01 | — | — | EP | disclosed |
| EP-1500385-B1 | METHOD OF FOAM STABILIZATION FOR FOAM COSMETIC | HAKUTO KK (JP) | 2008-06-25 | — | — | EP | disclosed |
| EP-1500385-A1 | METHOD OF FOAM STABILIZATION FOR FOAM COSMETIC | Hakuto Co., Ltd (JP) | 2005-01-26 | — | — | EP | disclosed |
| EP-1486193-A1 | METHOD OF STABILIZING SILICONE OIL-CONTAINING COSMETIC COMPOSITION | Hakuto Co., Ltd (JP) | 2004-12-15 | — | — | EP | disclosed |
| US-5395914-A | Nucleophilic polycondensation of hydroxy halogen xanthones | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-03-07 | — | — | US | disclosed |
| US-5296601-A | Reaction of aromatic chloride with carbon monoxide and alcohol | NIHON NOHYAKU CO., LTD. (JP) | 1994-03-22 | — | — | US | disclosed |
| EP-0571883-A1 | Polyarylethers with xanthone units, method for their production and their application | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-12-01 | — | — | EP | disclosed |
| EP-0282266-B1 | PROCESS FOR PRODUCING CARBOXYLIC ACID AMIDES OR ESTERS | NIHON NOHYAKU CO., LTD. (JP) | 1992-09-09 | — | — | EP | disclosed |
| US-5142057-A | Reacting an organic chloride with carbon monoxide and amine | NIHON NOHYAKU CO., LTD. (JP) | 1992-08-25 | — | — | US | disclosed |
| EP-0282266-A2 | Process for producing carboxylic acid amides or esters | NIHON NOHYAKU CO., LTD. (JP) | 1988-09-14 | — | — | EP | disclosed |
| US-4467035-A | Cultivation of phototrophic bacteria in the absence of ultraviolet light | NIPPON CARBIDE KOGYO KABUSHIKI KAISHA (JP) | 1984-08-21 | — | — | US | disclosed |