Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.38 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.32 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CETP | P11597 | 1/20 | 0.31 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.31 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26444829 | 0.73 | SLC22A6 (0.36) | GABRR1LMNASLC22A6TDP1SMN1; SMN2 | |
| SCHEMBL25242211 | 0.71 | SLC22A6 (0.35) | GABRR1LMNASLC22A6TDP1SMN1; SMN2 | |
| SCHEMBL14524724 | 0.71 | GABRR1 (0.32) | GABRR1LMNAGLRA1SLC6A9OR51E2 | |
| SCHEMBL11273231 | 0.71 | ADRA1A (0.32) | ADRA1A | |
| SCHEMBL21273013 | 0.70 | SLC22A6 (0.33) | SLC22A6TDP1SMN1; SMN2 | |
| SCHEMBL21273015 | 0.70 | SLC22A6 (0.33) | SLC22A6TDP1SMN1; SMN2 | |
| SCHEMBL28474842 | 0.68 | GABRR1 (0.46) | GABRR1LMNAGLRA1SLC6A9OR51E2 | |
| SCHEMBL15083296 | 0.67 | SLC22A6 (0.39) | GABRR1LMNAGLRA1SLC6A9OR51E2 | |
| SCHEMBL327489 | 0.67 | SLC22A6 (0.39) | GABRR1LMNAGLRA1SLC6A9OR51E2 | |
| SCHEMBL14533751 | 0.67 | SLC22A6 (0.39) | GABRR1LMNAGLRA1SLC6A9OR51E2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4325877-A | Production of intermediates for enzyme inhibitors | RICHARDSON-MERRELL INC. (US) | 1982-04-20 | — | — | US | disclosed |
| EP-0021883-A2 | N-acyl-amino acid derivatives and pharmaceutical compositions containing them, intermediates and starting compounds | MERRELL TORAUDE ET COMPAGNIE (FR) | 1981-01-07 | — | — | EP | disclosed |