Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11266712 | 1.00 | HDAC3 (0.41) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL11273028 | 0.74 | KDM4E (0.50) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Fumaric Acid SCHEMBL11269540 | 0.71 | SDCBP (0.46) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Fumaric Acid SCHEMBL11269551 | 0.71 | SDCBP (0.46) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Fumaric Acid SCHEMBL11130141 | 0.71 | SDCBP (0.46) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Fumaric Acid SCHEMBL11261354 | 0.71 | SDCBP (0.46) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Fumaric Acid SCHEMBL11130146 | 0.71 | SDCBP (0.46) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Fumaric Acid SCHEMBL11261365 | 0.71 | SDCBP (0.46) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL11275306 | 0.67 | SLC6A4 (0.47) | HPGDMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL11261318 | 0.67 | SLC6A4 (0.47) | HPGDMEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0053015-A1 | 1-Phenylthio-2-aminopropane derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1982-06-02 | — | — | EP | claimed |
| EP-0053015-A1 | 1-Phenylthio-2-aminopropane derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1982-06-02 | — | — | EP | disclosed |