SCHEMBL1126910

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1127128	0.93	AR (0.41)	ARGRIA4GRIA2KDM4EGAA
	SCHEMBL1126762	0.90	AR (0.43)	ARGRIA4GRIA2ALDH1A1MAPT
	SCHEMBL1127194	0.89	AR (0.43)	ARGRIA4GRIA2ALDH1A1MAPT
	SCHEMBL1126786	0.84	TSHR (0.50)	ARALDH1A1MAPTKDM4EHPGD
	SCHEMBL1127427	0.82	KDM4E (0.45)	ARGRIA4GRIA2ALDH1A1MAPT
	SCHEMBL1988958	0.82	KDM4E (0.49)	ARGRIA4GRIA2ALDH1A1MAPT
	SCHEMBL1127111	0.82	KDM4E (0.45)	ARGRIA4GRIA2ALDH1A1MAPT
	SCHEMBL1127403	0.80	MEN1 (0.49)	ARGRIA4GRIA2ALDH1A1MAPT
	SCHEMBL1127384	0.79	AR (0.46)	ARGRIA4GRIA2ALDH1A1HPGD
	SCHEMBL15161818	0.77	TSHR (0.48)	ARALDH1A1MAPTKDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.