SCHEMBL11269271

SCHEMBL11269271

O=C(O)C(=C(Cl)Cl)c1cc2ccccc2s1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCL2L1 Q07817 1/20 0.64
HDAC1 Q13547 2/20 0.56
HDAC3 O15379 1/20 0.56
HDAC4 P56524 1/20 0.56
HDAC7 Q8WUI4 1/20 0.56
HDAC2 Q92769 1/20 0.56
HDAC10 Q969S8 1/20 0.56
HDAC11 Q96DB2 1/20 0.56
HDAC8 Q9BY41 1/20 0.56
HDAC6 Q9UBN7 1/20 0.56
HDAC9 Q9UKV0 1/20 0.56
HDAC5 Q9UQL6 1/20 0.56
SLC9A1 P19634 2/20 0.50
HRH4 Q9H3N8 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
CNR1 P21554 1/20 0.49
CNR2 P34972 1/20 0.49
DYRK1A Q13627 1/20 0.49
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL103529 0.80 BCL2L1 (0.69) BCL2L1HDAC1HDAC3HDAC4HDAC7
SCHEMBL7639982 0.79 BCL2L1 (0.72) BCL2L1HDAC1HDAC3HDAC4HDAC7
SCHEMBL29438783 0.78 BCL2L1 (1.00) BCL2L1HDAC1HDAC3HDAC4HDAC7
SCHEMBL93858 0.78 BCL2L1 (1.00) BCL2L1HDAC1HDAC3HDAC4HDAC7
Hydrochloric Acid SCHEMBL443833 0.77 BCL2L1 (0.96) BCL2L1HDAC1HDAC3HDAC4HDAC7
SCHEMBL6321234 0.76 BCL2L1 (0.74) BCL2L1HDAC1HDAC3HDAC4HDAC7
SCHEMBL31356465 0.76 BCL2L1 (0.74) BCL2L1HDAC1HDAC3HDAC4HDAC7
SCHEMBL7209477 0.76 BCL2L1 (0.74) BCL2L1HDAC1HDAC3HDAC4HDAC7
SCHEMBL11270719 0.75 BCL2L1 (0.62) BCL2L1HDAC1HDAC3HDAC4HDAC7
SCHEMBL5355955 0.74 BCL2L1 (0.71) BCL2L1HDAC1HDAC3HDAC4HDAC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0048954-A2 Beta-lactam compounds, process for the preparation thereof and intermediate products for the preparation thereof SAGAMI CHEMICAL RESEARCH CENTER (JP) 1982-04-07 EP disclosed