Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | GALR2 | O43603 | 1/20 | 0.37 |
| ▸ | MPI | P34949 | 1/20 | 0.37 |
| ▸ | CCR6 | P51684 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2680731 | 0.80 | CYP3A4 (0.39) | MAPTMEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL217092 | 0.78 | ALDH1A1 (0.44) | MAPTHTTMEN1KMT2AMITF | |
| SCHEMBL5726490 | 0.78 | ALDH1A1 (0.44) | MAPTHTTMEN1KMT2AALDH1A1 | |
| SCHEMBL8448176 | 0.78 | ERN1 (0.42) | MAPTMEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL29965062 | 0.77 | CYP1A2 (0.46) | MAPTALDH1A1CYP3A4CYP1A2SMN1; SMN2 | |
| SCHEMBL4665919 | 0.74 | MEN1 (0.44) | MAPTHTTMEN1KMT2AMITF | |
| SCHEMBL9626194 | 0.74 | MAPT (0.44) | MAPTHTTMEN1KMT2AMITF | |
| SCHEMBL11948736 | 0.74 | PSMB8 (0.45) | MAPTHTTMEN1KMT2AMITF | |
| SCHEMBL11813443 | 0.72 | ALDH1A1 (0.42) | MAPTHTTMEN1KMT2AMITF | |
| SCHEMBL25344763 | 0.72 | GAA (0.38) | MAPTHTTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4366321-A | Preparation of 2-halo-3-nitro-5-acyl thiophenes and intermediate compounds | EASTMAN KODAK COMPANY (US) | 1982-12-28 | — | — | US | disclosed |