Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.36 |
| ▸ | CFTR | P13569 | 1/20 | 0.35 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.34 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15998725 | 0.80 | KDM4E (0.46) | KDM4EMAPTALDH1A1MEN1POLB | |
| SCHEMBL23900971 | 0.75 | KDM4E (0.47) | KDM4EMAPTALDH1A1MEN1POLB | |
| SCHEMBL23900972 | 0.74 | KDM4E (0.46) | KDM4EMAPTALDH1A1MEN1POLB | |
| SCHEMBL23587376 | 0.73 | MEN1 (0.46) | KDM4EMAPTALDH1A1MEN1POLB | |
| SCHEMBL2612448 | 0.73 | NPSR1 (0.57) | GAANPSR1CFTRGOPCLMNA | |
| SCHEMBL15688238 | 0.70 | GAA (0.41) | KDM4EMAPTALDH1A1MEN1POLB | |
| SCHEMBL5681418 | 0.69 | MAPK1 (0.37) | KDM4EMAPTALDH1A1KMT2AMAPK1 | |
| SCHEMBL38656253 | 0.69 | KDM4E (0.48) | KDM4EMAPTALDH1A1MEN1POLB | |
| SCHEMBL12231012 | 0.68 | GAA (0.45) | KDM4EMAPTALDH1A1MEN1POLB | |
| SCHEMBL2187057 | 0.67 | TRPM4 (0.56) | KDM4EMAPTALDH1A1MEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4333877-A | Substituted 2,7-dioxo-2,7-dihydrobenzo[1:2-b; 5:6-b1 ]difuran or -dipyrrole dyestuffs, their preparation and their use | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1982-06-08 | — | — | US | disclosed |
| EP-0023080-A1 | Substituted 2,7-dioxo-2,7-dihydrobenzo(1:2-b; 5,6-b1)difuran or dipyrrole dyestuffs, processes for their preparation and their use for the colouration of aromatic polyester textile materials | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1981-01-28 | — | — | EP | disclosed |