Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CCNC | P24863 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 8/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.36 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1988726 | 0.78 | CCNC (0.40) | ALDH1A1CYP1A2CCNCCDK8CNR2 | |
| SCHEMBL1127844 | 0.76 | KDM4E (0.41) | ALDH1A1CYP1A2POLBCCNCCDK8 | |
| SCHEMBL1126509 | 0.74 | HTR2A (0.42) | HTR6HTR2AHTR2CHTR1D | |
| SCHEMBL1126911 | 0.74 | HTR2C (0.41) | ALDH1A1CYP1A2POLBCNR2HTR6 | |
| SCHEMBL1126999 | 0.67 | ESR1 (0.48) | ALDH1A1CYP1A2POLBCCNCCDK8 | |
| SCHEMBL1127347 | 0.67 | CNR1 (0.50) | ALDH1A1CCNCCDK8CNR2USP2 | |
| SCHEMBL2834581 | 0.66 | CCNC (0.43) | ALDH1A1POLBCCNCCDK8KDM4E | |
| SCHEMBL30740984 | 0.64 | HTR2C (0.45) | ALDH1A1CYP1A2POLBCNR2HTR6 | |
| SCHEMBL1126815 | 0.64 | BRD4 (0.58) | ALDH1A1POLBCCNCCDK8KDM4E | |
| SCHEMBL1127225 | 0.63 | CCNC (0.41) | ALDH1A1CCNCCDK8KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283006-B1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2015-02-25 | — | — | EP | disclosed |
| EP-2626361-B1 | Pyrrole antifungal agents | F2G LTD (GB) | 2014-10-15 | — | — | EP | disclosed |
| EP-2626361-A1 | Pyrrole antifungal agents | F2G Limited (GB) | 2013-08-14 | — | — | EP | disclosed |
| EP-2283006-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G Limited (GB) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009130481-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2009-10-29 | — | — | WO | disclosed |