Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | HTR1D | P28221 | 2/20 | 0.38 |
| ▸ | HTR6 | P50406 | 4/20 | 0.37 |
| ▸ | HTR7 | P34969 | 3/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1127046 | 0.82 | CNR1 (0.46) | ALDH1A1KDM4ELMNAMAPK1CNR2 | |
| SCHEMBL1126995 | 0.78 | GFER (0.39) | ALDH1A1KDM4ESMN1; SMN2MAPK1CYP1A2 | |
| SCHEMBL1127684 | 0.77 | ALDH1A1 (0.41) | ALDH1A1KDM4ESMN1; SMN2CYP1A2POLB | |
| SCHEMBL15162305 | 0.76 | KDM4E (0.46) | ALDH1A1KDM4ESMN1; SMN2LMNAMAPT | |
| SCHEMBL1127023 | 0.74 | ALDH1A1 (0.58) | ALDH1A1KDM4ESMN1; SMN2MAPTCYP1A2 | |
| SCHEMBL1126958 | 0.74 | ALDH1A1 (0.40) | HTR2CHTR2AALDH1A1KDM4EHTR1D | |
| SCHEMBL15162449 | 0.70 | ALDH1A1 (0.42) | HTR2AALDH1A1KDM4EHTR6HTR7 | |
| SCHEMBL30740984 | 0.70 | HTR2C (0.45) | HTR2CHTR2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL1126989 | 0.69 | ALDH1A1 (0.39) | ALDH1A1CYP1A2CNR2 | |
| SCHEMBL1126731 | 0.67 | MMP1 (0.41) | ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283006-B1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2015-02-25 | — | — | EP | disclosed |
| EP-2626361-B1 | Pyrrole antifungal agents | F2G LTD (GB) | 2014-10-15 | — | — | EP | disclosed |
| EP-2626361-A1 | Pyrrole antifungal agents | F2G Limited (GB) | 2013-08-14 | — | — | EP | disclosed |
| EP-2283006-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G Limited (GB) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009130481-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2009-10-29 | — | — | WO | disclosed |