⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Urea SCHEMBL6684771 | 0.94 | — | — | |
| Urea SCHEMBL390330 | 0.94 | — | — | |
| Urea SCHEMBL4393055 | 0.88 | — | — | |
| Urea SCHEMBL5035236 | 0.88 | — | — | |
| Urea SCHEMBL11630935 | 0.88 | — | — | |
| Urea SCHEMBL8560069 | 0.87 | LMNA (1.00) | — | |
| Urea SCHEMBL8436158 | 0.87 | LMNA (1.00) | — | |
| Urea SCHEMBL8434002 | 0.87 | LMNA (1.00) | — | |
| Urea SCHEMBL20641124 | 0.87 | LMNA (1.00) | — | |
| Urea SCHEMBL7756359 | 0.87 | LMNA (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4361558-A | PREPARATION OF THESE ANTIINFLAMMATORY AGENTS | CIBA-GEIGY CORPORATION (US) | 1982-11-30 | — | — | US | disclosed |
| US-4310466-A | ANTIINFLAMMATORY STEROIDS | SYNTEX (U.S.A.) INC. (US) | 1982-01-12 | — | — | US | disclosed |
| US-4273770-A | CORTICOIDS, ANTIINFLAMMATORY AGENTS | SYNTEX (U.S.A.) INC. (US) | 1981-06-16 | — | — | US | disclosed |
| EP-0004773-B1 | 17-BETA-THIOCARBOXYLIC ACID ESTERS OF 4-HALO-3-OXOANDROST-4-ENES, THEIR PHARMACEUTICAL USE AND PROCESSES FOR THEIR PREPARATION | SYNTEX (U.S.A.) INC. (US) | 1981-04-29 | — | — | EP | disclosed |
| US-4263289-A | ANTIINFLAMMATORY STEROIDS | SYNTEX (U.S.A.) INC. (US) | 1981-04-21 | — | — | US | disclosed |
| US-4261986-A | ANTIINFLAMMATORY STEROIDS | SYNTEX (U.S.A.) INC. (US) | 1981-04-14 | — | — | US | disclosed |
| US-4198336-A | Chemical process for preparing androsta-4-ene 17α-carboxylic acids | SYNTEX (U.S.A.) INC. (US) | 1980-04-15 | — | — | US | disclosed |
| US-4198404-A | ANTIINFLAMMATORY STEROIDS | SYNTEX (U.S.A.) INC. (US) | 1980-04-15 | — | — | US | disclosed |
| US-4188385-A | ANTIINFLAMMATORY STERIODS | SYNTEX (U.S.A.) INC. (US) | 1980-02-12 | — | — | US | disclosed |
| US-4187301-A | ANTIINFLAMMATORY AGENTS | SYNTEX (U.S.A.) INC. (US) | 1980-02-05 | — | — | US | disclosed |
| EP-0004741-A2 | Thio etianic acid derivatives, their preparation and pharmaceutical use | SYNTEX (U.S.A.) INC. (US) | 1979-10-17 | — | — | EP | disclosed |
| EP-0004773-A2 | 17-Beta-thiocarboxylic acid esters of 4-halo-3-oxoandrost-4-enes, their pharmaceutical use and processes for their preparation | SYNTEX (U.S.A.) INC. (US) | 1979-10-17 | — | — | EP | disclosed |
| EP-0004772-A2 | 4-Halo etianic acids and derivatives thereof, their pharmaceutical use and preparation | SYNTEX (U.S.A.) INC. (US) | 1979-10-17 | — | — | EP | disclosed |
| EP-0004766-A2 | 4-Halo-pregn-4-enes, their preparation and pharmaceutical use | SYNTEX (U.S.A.) INC. (US) | 1979-10-17 | — | — | EP | disclosed |