Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Urea. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Urea SCHEMBL6684771 | 0.94 | — | — | |
| Urea SCHEMBL28478547 | 0.94 | LMNA (0.86) | — | |
| Urea SCHEMBL390330 | 0.94 | — | — | |
| Urea SCHEMBL6361905 | 0.88 | — | — | |
| Urea SCHEMBL11594201 | 0.88 | — | — | |
| Urea SCHEMBL23779965 | 0.88 | — | — | |
| Urea SCHEMBL10948406 | 0.88 | — | — | |
| Urea SCHEMBL10413304 | 0.88 | — | — | |
| Urea SCHEMBL11269754 | 0.88 | — | — | |
| Urea SCHEMBL11590334 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3245501-B1 | APPARATUS FOR, SYSTEM FOR AND METHOD OF MAINTAINING SENSOR ACCURACY | ECOLAB USA INC (US) | 2020-03-04 | — | — | EP | claimed |
| US-10481127-B2 | Apparatus for, system for and methods of maintaining sensor accuracy | ECOLAB USA INC. (US) | 2019-11-19 | — | — | US | claimed |
| US-20180017522-A1 | Apparatus for, System for and Methods of Maintaining Sensor Accuracy | ECOLAB USA INC. (US) | 2018-01-18 | — | — | US | claimed |
| EP-3245501-A1 | APPARATUS FOR, SYSTEM FOR AND METHOD OF MAINTAINING SENSOR ACCURACY | Ecolab USA Inc. (US) | 2017-11-22 | — | — | EP | claimed |
| US-9772303-B2 | Apparatus for, system for and methods of maintaining sensor accuracy | ECOLAB USA INC. (US) | 2017-09-26 | — | — | US | claimed |
| WO-2016115069-A1 | APPARATUS FOR, SYSTEM FOR AND METHOD OF MAINTAINING SENSOR ACCURACY | ECOLAB USA INC. (US) | 2016-07-21 | — | — | WO | claimed |
| US-20160202155-A1 | Apparatus for, System for and Methods of Maintaining Sensor Accuracy | ECOLAB USA INC. (US) | 2016-07-14 | — | — | US | claimed |
| US-20240174665-A1 | CDK2 INHIBITORS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2024-05-30 | — | — | US | disclosed |
| US-20240173419-A1 | CDK2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2024-05-30 | — | — | US | disclosed |
| US-20240164377-A1 | LOW VOLATILITY PROMOTING WATER CONDITIONING ADJUVANTS | ADJUVANTS UNLIMITED LLC (US) | 2024-05-23 | — | — | US | disclosed |
| CN-117715904-A | CDK2 degrading agents and uses thereof | 凯麦拉医疗公司 | 2024-03-15 | — | — | CN | disclosed |
| EP-4334307-A1 | CDK2 DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2024-03-13 | — | — | EP | disclosed |
| WO-2024039901-A2 | CDK2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2024-02-22 | — | — | WO | disclosed |
| WO-2016115073-A1 | APPARATUS FOR MAINTAINING SENSOR ACCURACY | ECOLAB USA INC. (US) | 2016-07-21 | — | — | WO | disclosed |
| US-20160202229-A1 | Apparatus for, System for and Methods of Maintaining Sensor Accuracy | ECOLAB USA INC. (US) | 2016-07-14 | — | — | US | disclosed |
| US-20160202155-A1 | Apparatus for, System for and Methods of Maintaining Sensor Accuracy | ECOLAB USA INC. (US) | 2016-07-14 | — | — | US | disclosed |
| WO-2016015056-A1 | LOW VOLATILITY PROMOTING WATER CONDITIONING ADJUVANTS | ADJUVANTS UNLIMITED LLC (US) | 2016-01-28 | — | — | WO | disclosed |
| US-8834970-B2 | Method and composition for enhancing the cure of resin-based coatings | TREMCO BARRIER SOLUTIONS, INC. (US) | 2014-09-16 | — | — | US | disclosed |
| US-20080099721-A1 | Preliminary cure of an aqueous acrylic weatherproofing emulsion coating is accelerated by contacting the coating with urea hydrochloride dissolved in water; creates a thicker and tougher resin skin on the still-wet emulsion coating | TREMCO ACQUISITION, LLC | 2008-05-01 | — | — | US | disclosed |
| US-5672279-A | Method for using urea hydrochloride | PEACH STATE LABS, INC. (US) | 1997-09-30 | — | — | US | disclosed |