Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMOX1 | P09601 | 2/20 | 0.41 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.39 |
| ▸ | CYP21A2 | P08686 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | FNTA | P49354 | 3/20 | 0.39 |
| ▸ | FNTB | P49356 | 3/20 | 0.39 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | GRM6 | O15303 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11259885 | 0.90 | CYP2C9 (0.40) | HMOX1CYP17A1CYP21A2CYP11B1FNTA | |
| SCHEMBL11258654 | 0.90 | HMOX1 (0.42) | HMOX1CYP17A1CYP21A2CYP11B1FNTA | |
| SCHEMBL11257264 | 0.90 | CYP17A1 (0.38) | HMOX1CYP17A1CYP21A2CYP11B1FNTA | |
| SCHEMBL11262690 | 0.88 | ADRA2C (0.44) | HMOX1CYP17A1CYP21A2CYP11B1FNTA | |
| SCHEMBL11255611 | 0.86 | HMOX1 (0.56) | HMOX1 | |
| SCHEMBL11260891 | 0.85 | HMOX1 (0.43) | HMOX1CYP17A1CYP21A2CYP11B1FNTA | |
| SCHEMBL11259912 | 0.84 | HMOX1 (0.41) | HMOX1CYP17A1CYP21A2CYP11B1FNTA | |
| SCHEMBL11272980 | 0.84 | FNTA (0.39) | CYP17A1FNTAFNTBPGGT1BCYP2C9 | |
| SCHEMBL11256372 | 0.83 | HMOX1 (0.39) | HMOX1CYP17A1CYP21A2CYP11B1FNTA | |
| SCHEMBL11262884 | 0.83 | CYP11B1 (0.35) | HMOX1CYP11B1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4359475-A | SPERMICIDES, MICROBIOCIDES OR ANTICONVULSANTS | SYNTEX (U.S.A.) INC. (US) | 1982-11-16 | — | — | US | disclosed |