Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 4/20 | 0.37 |
| ▸ | MAOB | P27338 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10962220 | 0.79 | MAOB (0.49) | MEN1KMT2ACYP19A1ALDH1A1NPC1 | |
| SCHEMBL2348342 | 0.78 | ALDH1A1 (0.47) | MEN1MAPTKMT2ACYP19A1ALDH1A1 | |
| SCHEMBL696080 | 0.78 | MAOB (0.58) | MEN1MAPTKMT2ACYP19A1ALDH1A1 | |
| SCHEMBL10961375 | 0.76 | MAPT (0.46) | MAPTCYP19A1L3MBTL1MAOAMAOB | |
| SCHEMBL10963283 | 0.75 | MAOB (0.52) | MEN1MAPTKMT2ACYP19A1ALDH1A1 | |
| SCHEMBL2708071 | 0.73 | AAK1 (0.42) | MEN1MAPTKMT2ACYP19A1ALDH1A1 | |
| SCHEMBL30963727 | 0.72 | ALDH1A1 (0.55) | MEN1MAPTKMT2ACYP19A1ALDH1A1 | |
| SCHEMBL12215895 | 0.72 | ALDH1A1 (0.55) | MEN1MAPTKMT2ACYP19A1ALDH1A1 | |
| SCHEMBL10964913 | 0.71 | IMPDH2 (0.42) | KMT2AALDH1A1RAB9AMAOAMAOB | |
| SCHEMBL15395907 | 0.71 | MEN1 (0.39) | MEN1MAPTKMT2ACYP19A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4320061-A | ANTISPASMODIC AGENTS | KALI-CHEMIE PHARMA GMBH (DE) | 1982-03-16 | — | — | US | disclosed |
| US-4279905-A | GASTROINTESTINAL DISORDERS | KALI-CHEMIE PHARMA GMBH (DE) | 1981-07-21 | — | — | US | disclosed |
| EP-0025109-A2 | 1-Benzoxepin-5(2H)-one derivatives and their salts, and processes for their preparation | Kali-Chemie Pharma GmbH (DE) | 1981-03-18 | — | — | EP | disclosed |