Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | ERCC5 | P28715 | 4/20 | 0.47 |
| ▸ | FEN1 | P39748 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | P4HB | P07237 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2263377 | 0.83 | CTNNB1 (0.54) | KDM4EALDH1A1ERCC5FEN1KMT2A | |
| SCHEMBL7671012 | 0.83 | KDM4E (0.53) | KDM4EALDH1A1EGLN2CA12CA1 | |
| SCHEMBL29819613 | 0.82 | KMT2A (0.61) | KDM4EALDH1A1ERCC5FEN1KMT2A | |
| SCHEMBL20239513 | 0.82 | KMT2A (0.61) | KDM4EALDH1A1ERCC5FEN1KMT2A | |
| SCHEMBL20487359 | 0.82 | KDM4E (0.54) | KDM4EALDH1A1ERCC5FEN1KMT2A | |
| SCHEMBL8231217 | 0.82 | ERCC5 (0.69) | KDM4EALDH1A1ERCC5FEN1KMT2A | |
| SCHEMBL2200555 | 0.82 | L3MBTL1 (0.50) | KDM4EALDH1A1ERCC5FEN1KMT2A | |
| SCHEMBL5482399 | 0.82 | ERCC5 (0.46) | KDM4EALDH1A1ERCC5FEN1KMT2A | |
| SCHEMBL5898776 | 0.81 | FEN1 (0.67) | KDM4EALDH1A1EGLN2CA12CA1 | |
| SCHEMBL1109662 | 0.80 | ERCC5 (0.64) | KDM4EALDH1A1ERCC5FEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3589630-B1 | CYCLIC SULFAMIDE COMPOUNDS AND METHODS OF USING SAME | ASSEMBLY BIOSCIENCES INC (US) | 2021-07-07 | — | — | EP | disclosed |
| US-4315932-A | AND SULFANILAMIDES | BURROUGHS WELLCOME CO. (US) | 1982-02-16 | — | — | US | disclosed |
| EP-0000541-B1 | 1H-PYRIMIDO-(4,5-C)-1,2-DIAZEPINES, METHODS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM; THEIR USE AS INTERMEDIATES FOR HETEROCYCLIC TRANSFORMATIONS. | THE WELLCOME FOUNDATION LIMITED (GB) | 1982-02-03 | — | — | EP | disclosed |
| US-4288365-A | 1H-PYRIMIDO(4,5-C)-1,2-DIAZEPINES | BURROUGHS WELLCOME CO. (US) | 1981-09-08 | — | — | US | disclosed |
| US-4260758-A | MICROBIOCIDES | BURROUGHS WELLCOME CO. (US) | 1981-04-07 | — | — | US | disclosed |
| US-4237289-A | MICROBIOCIDES | BURROUGHS WELLCOME CO. (US) | 1980-12-02 | — | — | US | disclosed |
| EP-0000541-A2 | 1H-Pyrimido-(4,5-c)-1,2-diazepines, methods for their preparation and compositions containing them; their use as intermediates for heterocyclic transformations. | THE WELLCOME FOUNDATION LIMITED (GB) | 1979-02-07 | — | — | EP | disclosed |