Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11266948 | 0.81 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2LMNAMAPTGAA | |
| SCHEMBL11363999 | 0.81 | DRD2 (0.51) | — | |
| Phosphoric Acid SCHEMBL11257050 | 0.79 | DRD2 (0.49) | — | |
| SCHEMBL11364002 | 0.79 | ALDH1A1 (0.38) | POLBMAPK1ALDH1A1SMN1; SMN2LMNA | |
| Phosphoric Acid SCHEMBL11257055 | 0.77 | ALDH1A1 (0.37) | POLBMAPK1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL27311891 | 0.69 | ALDH1A1 (0.62) | POLBMAPK1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL11259209 | 0.68 | MEN1 (0.47) | POLBALDH1A1SMN1; SMN2GAARAB9A | |
| SCHEMBL10260134 | 0.67 | SMN1; SMN2 (0.85) | POLBMAPK1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL11270751 | 0.66 | ALDH1A1 (0.40) | POLBMAPK1ALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL14484970 | 0.66 | POLB (0.67) | POLBMAPK1ALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4323503-A | PSYCHOFUNCTION PROPERTIES SUCH AS ANXIOLYTIC OR PSYCHOSTIMULANT | SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE-DE-FRANCE (FR) | 1982-04-06 | — | — | US | claimed |
| US-4323503-A | PSYCHOFUNCTION PROPERTIES SUCH AS ANXIOLYTIC OR PSYCHOSTIMULANT | SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE-DE-FRANCE (FR) | 1982-04-06 | — | — | US | disclosed |
| US-4306072-A | ANXIOLYTIC AND PSYCHOSTIMULANT ACTIVITY FOR TREATMENT OF PSYCHOLOGICAL DISORDERS | SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE (FR) | 1981-12-15 | — | — | US | disclosed |
| US-4268512-A | ANXIOLYTIC AGENTS, PSYCHOSTIMULANTS | SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE-DE-FRANCE (FR) | 1981-05-19 | — | — | US | disclosed |
| US-4255580-A | TREATMENT OF PSYCHOLOGICAL DISORDERS | SIOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE-DE-FRANCE (FR) | 1981-03-10 | — | — | US | disclosed |
| US-4248885-A | FOR GASTROINTESTINAL, UROGENITAL, RHEUMATIC, AND CARDIOVASCULAR DISEASE | SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE-DE-FRANCE (FR) | 1981-02-03 | — | — | US | disclosed |
| US-4186135-A | TREATMENT OF PSYCHOLOGICAL DISORDERS | SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE-DE-FRANCE (FR) | 1980-01-29 | — | — | US | disclosed |