Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | PYGL | P06737 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 2/20 | 0.39 |
| ▸ | JAK1 | P23458 | 2/20 | 0.39 |
| ▸ | TYK2 | P29597 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | GCGR | P47871 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | GHSR | Q92847 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11281809 | 0.88 | MAPT (0.50) | RAB9ANPC1NPSR1CYP3A4MAPT | |
| SCHEMBL11275106 | 0.84 | NPY5R (0.45) | RAB9ANPC1NPSR1KDRMAPT | |
| SCHEMBL11278901 | 0.80 | HTT (0.46) | PTGESNR3C1RAB9ANPC1NPSR1 | |
| Dichlorbenzuron SCHEMBL3663126 | 0.77 | CNR1 (0.54) | CNR1PYGLRAB9ANPC1NPSR1 | |
| SCHEMBL11281897 | 0.74 | RXFP1 (0.48) | RAB9ANPC1KDRMAPTMAPK14 | |
| SCHEMBL11273766 | 0.74 | SMN1; SMN2 (0.47) | PTGESRAB9ANPC1NPSR1MAPT | |
| SCHEMBL11281937 | 0.74 | TDP1 (0.47) | PYGLRAB9ANPC1NPSR1GCGR | |
| SCHEMBL30499670 | 0.72 | KMT2A (0.67) | PYGLRAB9ANPC1NPSR1KDR | |
| SCHEMBL9352522 | 0.72 | KMT2A (0.67) | PYGLRAB9ANPC1NPSR1KDR | |
| SCHEMBL11176926 | 0.72 | TRPV1 (0.45) | CNR1PYGLRAB9ANPC1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4366155-A | 1-Benzoyl-3-(6-oxopyridazinyl)ureas, compositions, and insecticidal method | ELI LILLY AND COMPANY (US) | 1982-12-28 | — | — | US | claimed |
| EP-0063413-A1 | 1-Benzoyl-3-(heterocyclic)ureas, compositions, and insecticidal method | ELI LILLY AND COMPANY (US) | 1982-10-27 | — | — | EP | claimed |
| US-4366155-A | 1-Benzoyl-3-(6-oxopyridazinyl)ureas, compositions, and insecticidal method | ELI LILLY AND COMPANY (US) | 1982-12-28 | — | — | US | disclosed |
| EP-0063413-A1 | 1-Benzoyl-3-(heterocyclic)ureas, compositions, and insecticidal method | ELI LILLY AND COMPANY (US) | 1982-10-27 | — | — | EP | disclosed |