Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.43 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11281897 | 0.92 | RXFP1 (0.48) | TDP1GAAPLCG2MAPTNPC1 | |
| SCHEMBL8669219 | 0.83 | GAA (0.46) | TDP1GAAMAPTTHRBP2RX1 | |
| SCHEMBL11275106 | 0.82 | NPY5R (0.45) | GAAMAPTNPC1RAB9AMEN1 | |
| SCHEMBL9135913 | 0.82 | GAA (0.45) | TDP1GAAMAPTTHRBP2RX1 | |
| SCHEMBL11319276 | 0.76 | GAA (0.45) | TDP1GAAPLCG2MAPTTHRB | |
| SCHEMBL11283145 | 0.76 | MAPK14 (0.47) | GAAMAPTRXFP1PKMMEN1 | |
| SCHEMBL11286418 | 0.76 | RXFP1 (0.46) | TDP1GAAMAPTRXFP1MEN1 | |
| Chlotrifmeuron SCHEMBL10868747 | 0.75 | TDP1 (0.70) | TDP1GAAPLCG2MAPTNPC1 | |
| SCHEMBL11273034 | 0.74 | SMN1; SMN2 (0.41) | GAAMAPTTHRBNPC1RAB9A | |
| SCHEMBL11269918 | 0.74 | PTGES (0.42) | MAPTNPC1RAB9AGCGRPYGL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0063413-A1 | 1-Benzoyl-3-(heterocyclic)ureas, compositions, and insecticidal method | ELI LILLY AND COMPANY (US) | 1982-10-27 | — | — | EP | claimed |
| US-4366155-A | 1-Benzoyl-3-(6-oxopyridazinyl)ureas, compositions, and insecticidal method | ELI LILLY AND COMPANY (US) | 1982-12-28 | — | — | US | disclosed |
| EP-0063413-A1 | 1-Benzoyl-3-(heterocyclic)ureas, compositions, and insecticidal method | ELI LILLY AND COMPANY (US) | 1982-10-27 | — | — | EP | disclosed |