Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 7/20 | 0.45 |
| ▸ | CCR1 | P32246 | 4/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11281897 | 0.90 | RXFP1 (0.48) | NPY5RCCR1MAPK14MAPTSMN1; SMN2 | |
| SCHEMBL11269918 | 0.84 | PTGES (0.42) | MAPK14MAPTNPSR1KDRNPC1 | |
| SCHEMBL11273156 | 0.83 | MAPK14 (0.49) | NPY5RCCR1MAPK14MAPTSMN1; SMN2 | |
| SCHEMBL11270873 | 0.83 | MAPK14 (0.46) | NPY5RCCR1MAPK14MAPTNPBWR1 | |
| SCHEMBL11287046 | 0.82 | MAPK14 (0.52) | NPY5RMAPK14MAPTSMN1; SMN2MEN1 | |
| SCHEMBL11281937 | 0.82 | TDP1 (0.47) | CCR1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL11281809 | 0.80 | MAPT (0.50) | MAPK14MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL7603216 | 0.78 | KDR (0.66) | MAPTSMN1; SMN2MEN1KMT2ANPSR1 | |
| SCHEMBL30499683 | 0.78 | KDR (0.66) | MAPTSMN1; SMN2MEN1KMT2ANPSR1 | |
| SCHEMBL11276599 | 0.77 | TLR7 (0.43) | CCR1MAPK14MAPTSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0063413-A1 | 1-Benzoyl-3-(heterocyclic)ureas, compositions, and insecticidal method | ELI LILLY AND COMPANY (US) | 1982-10-27 | — | — | EP | claimed |
| US-4366155-A | 1-Benzoyl-3-(6-oxopyridazinyl)ureas, compositions, and insecticidal method | ELI LILLY AND COMPANY (US) | 1982-12-28 | — | — | US | disclosed |
| EP-0063413-A1 | 1-Benzoyl-3-(heterocyclic)ureas, compositions, and insecticidal method | ELI LILLY AND COMPANY (US) | 1982-10-27 | — | — | EP | disclosed |