SCHEMBL11270154

SCHEMBL11270154

CCNCc1ccc[nH]1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31703898 0.86 MAOA (0.38)
SCHEMBL13280554 0.82 MEN1 (0.41)
SCHEMBL28386140 0.79 HTR2A (0.45)
SCHEMBL13280691 0.78 CA12 (0.39)
SCHEMBL6265659 0.77
SCHEMBL163556 0.76
SCHEMBL1230828 0.75 MC4R (0.41)
SCHEMBL28677353 0.75 MEN1 (0.50)
SCHEMBL588497 0.75
SCHEMBL22593354 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119504547-A Amisulpride preparation method of the composition 山东安弘制药有限公司 2025-02-25 CN claimed
CN-113735755-B Preparation method of amisulpride 深圳市新浩瑞医药科技有限公司 2024-05-31 CN claimed
CN-113735755-A Preparation method of amisulpride 深圳市新浩瑞医药科技有限公司 2021-12-03 CN claimed
JP-55002650-A None JP disclosed
CN-119504547-A Amisulpride preparation method of the composition 山东安弘制药有限公司 2025-02-25 CN disclosed
CN-119504547-A Amisulpride preparation method of the composition 山东安弘制药有限公司 2025-02-25 CN disclosed
EP-4139308-B1 PURINE DERIVATIVES AS DRUGS FOR THE TREATMENT OF NEONATAL HYPOXIA-ISCHEMIA BRAIN INJURY AND RELATED DISEASES COMMISSARIAT ENERGIE ATOMIQUE (FR) 2024-07-17 EP disclosed
CN-113735755-B Preparation method of amisulpride 深圳市新浩瑞医药科技有限公司 2024-05-31 CN disclosed
CN-117185977-A Preparation method of amisulpride intermediate 江苏阿尔法药业股份有限公司 2023-12-08 CN disclosed
WO-2023066338-A1 SCM-38 MOLECULAR SIEVE, PREPARATION METHOD THEREFOR, AND USE THEREOF 中国石油化工股份有限公司 2023-04-27 WO disclosed
CN-113735755-A Preparation method of amisulpride 深圳市新浩瑞医药科技有限公司 2021-12-03 CN disclosed
WO-2021183970-A1 NON-ATP/CATALYTIC SITE P38 MITOGEN ACTIVATED PROTEIN KINASE INHIBITORS UNIVERSITY OF MARYLAND, BALTIMORE (US) 2021-09-16 WO disclosed
WO-2020118194-A1 NON-ATP/CATALYTIC SITE p38 MITOGEN ACTIVATED PROTEIN KINASE INHIBITORS UNIVERSITY OF MARYLAND, BALTIMORE (US) 2020-06-11 WO disclosed
WO-2016089830-A1 NOVEL TRICYCLIC COMPOUNDS AS INHIBITORS OF MUTANT IDH ENZYMES MERCK SHARP & DOHME CORP. (US) 2016-06-09 WO disclosed
US-4341707-A CHEMICAL INTERMEDIATES; PEPTIDE SYNTHESIS Ogura, Haruo (JP) 1982-07-27 US disclosed
JP-S552650-A HETEROCYCLIC BENZAMIDE COMPOUND AND ITS PREPARATION TEIKOKU CHEM IND CORP LTD 1980-01-10 JP disclosed
US-3980788-A XANTHENYL COMPOUNDS SMITHKLINE CORPORATION (US) 1976-09-14 US disclosed