Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31703898 | 0.87 | MAOA (0.38) | MAOA | |
| SCHEMBL16730446 | 0.81 | SLC6A2 (0.32) | MEN1KMT2AMAOA | |
| SCHEMBL13280554 | 0.79 | MEN1 (0.41) | MEN1KMT2ATDP1MAOAHRH4 | |
| Benzene SCHEMBL11697595 | 0.78 | MEN1 (0.78) | MEN1KMT2ATDP1MAOATHRB | |
| SCHEMBL1654 | 0.78 | MEN1 (0.78) | MEN1KMT2ATDP1MAOATHRB | |
| SCHEMBL5799878 | 0.78 | MEN1 (0.78) | MEN1KMT2ATDP1MAOATHRB | |
| Pyrrole SCHEMBL3880770 | 0.76 | MEN1 (0.61) | MEN1KMT2ATDP1MAOATHRB | |
| SCHEMBL13280691 | 0.75 | CA12 (0.39) | MAOACHRM2 | |
| SCHEMBL11270154 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL1862144 | 0.75 | MEN1 (0.74) | MEN1KMT2ATDP1MAOATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109336887-B | Benzimidazole chiral heterocyclic compound and preparation method and application thereof | 中山大学 | 2021-12-17 | — | — | CN | claimed |
| CN-109336887-B | Benzimidazole chiral heterocyclic compound and preparation method and application thereof | 中山大学 | 2021-12-17 | — | — | CN | disclosed |