Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TYR | P14679 | 1/20 | 0.45 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4373000 | 0.90 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL18315855 | 0.87 | SMN1; SMN2 (0.38) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL29413912 | 0.85 | POLB (0.36) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL8519938 | 0.85 | POLB (0.36) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL5196643 | 0.85 | SMN1; SMN2 (0.43) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL11056754 | 0.83 | SMN1; SMN2 (0.42) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL11651622 | 0.82 | RAPGEF4 (0.35) | ALDH1A1CA2POLBGLAMAPT | |
| SCHEMBL3671836 | 0.81 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL1664850 | 0.79 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL7638739 | 0.78 | SMN1; SMN2 (0.39) | SMN1; SMN2ALDH1A1CA2POLBTYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4348308-A | IMPROVING COLOR STABILITY OF VINYL CHLORIDE POLYMERS | ADEKA ARGUS CHEMICAL CO., LTD. (JP) | 1982-09-07 | — | — | US | disclosed |
| US-4309335-A | THERMAL AGING RESISTANCE; ORTHO-SUBSTITUTED PHENYL ACID PHOSPHITE | ADEKA ARGUS CHEMICAL CO., LTD. | 1982-01-05 | — | — | US | disclosed |
| US-4282141-A | DISCOLORATION INHIBITION FOR VINYL CHLORIDE POLYMERS | ARGUS CHEMICAL CORPORATION (US) | 1981-08-04 | — | — | US | disclosed |