Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11347478 | 0.82 | ALDH1A1 (0.40) | GAAALDH1A1GRIN1POLB | |
| SCHEMBL4183536 | 0.81 | MAPT (0.47) | GSK3BALDH1A1CYP3A4MAPT | |
| SCHEMBL11359163 | 0.81 | HDAC8 (0.50) | ALDH1A1 | |
| SCHEMBL11270285 | 0.79 | GLA (0.60) | GAAGSK3BBACE1ALDH1A1CYP3A4 | |
| SCHEMBL5755254 | 0.77 | CTSD (0.40) | GAAALDH1A1GRIN1TRPA1POLB | |
| SCHEMBL3634313 | 0.73 | EPHX2 (0.48) | CYP3A4GRIN1IDO1TP53TRPA1 | |
| SCHEMBL17296085 | 0.72 | SLC6A2 (0.41) | IDO1TRPA1 | |
| SCHEMBL5846563 | 0.72 | EPHX2 (0.42) | CYP3A4GRIN1TP53 | |
| SCHEMBL14492200 | 0.71 | GSK3B (0.53) | GAAGSK3BBACE1ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL17296112 | 0.71 | SLC6A2 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009005647-A2 | COMPOUNDS AND PROCESS TO PREPARE CHIRAL INTERMEDIATES FOR SYNTHESIS OF PAROXETINE | BIOVERDANT, INC. (US) | 2009-01-08 | — | — | WO | disclosed |