Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.45 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8746689 | 0.83 | ALDH1A1 (0.54) | ALDH1A1MAPTPOLBMEN1KMT2A | |
| SCHEMBL8746687 | 0.83 | ALDH1A1 (0.64) | ALDH1A1MAPTPOLBMEN1KMT2A | |
| SCHEMBL10741564 | 0.79 | IDO1 (0.54) | ALDH1A1MAPTPOLBMEN1KMT2A | |
| SCHEMBL74124 | 0.79 | ALDH1A1 (0.56) | ALDH1A1MAPTPOLBMEN1KMT2A | |
| SCHEMBL3646086 | 0.79 | MAPT (0.51) | ALDH1A1MAPTPOLBMEN1KMT2A | |
| SCHEMBL2026375 | 0.79 | MAPT (0.51) | ALDH1A1MAPTPOLBMEN1KMT2A | |
| SCHEMBL10498215 | 0.79 | MAPT (0.47) | ALDH1A1MAPTPOLBMEN1KMT2A | |
| SCHEMBL9570633 | 0.78 | MAPT (0.58) | ALDH1A1MAPTPOLBMEN1KMT2A | |
| Methane SCHEMBL27642737 | 0.78 | MAPT (0.50) | ALDH1A1MAPTPOLBMEN1KMT2A | |
| SCHEMBL7297643 | 0.78 | MAPT (0.58) | ALDH1A1MAPTPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107266275-B | Compound containing monofluoromethyl, preparation method and application thereof | 中国科学院上海有机化学研究所 | 2020-07-07 | — | — | CN | disclosed |
| US-4348411-A | Combating bacteria with halogenomethylsulphonylphenyl-phthalamic acids | BAYER AKTIENGESELLSCHAFT (DE) | 1982-09-07 | — | — | US | disclosed |