Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.38 |
| ▸ | HMOX1 | P09601 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | QPCT | Q16769 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11263880 | 0.95 | CYP2A6 (0.39) | CYP2A6CYP19A1CYP11B1CYP11B2CYP2B6 | |
| SCHEMBL11261707 | 0.92 | QPCT (0.39) | CYP19A1CYP11B1CYP11B2ALDH1A1QPCT | |
| SCHEMBL11259161 | 0.91 | TBXAS1 (0.38) | CYP19A1CYP11B1CYP11B2ALDH1A1QPCT | |
| SCHEMBL11265125 | 0.91 | CYP2A6 (0.39) | CYP2A6CYP19A1CYP11B1CYP11B2CYP2B6 | |
| SCHEMBL11266925 | 0.90 | HMOX1 (0.41) | CYP2A6CYP19A1CYP11B1CYP11B2CYP2B6 | |
| SCHEMBL11265536 | 0.89 | MEN1 (0.43) | CYP19A1ALDH1A1TP53QPCT | |
| SCHEMBL11260829 | 0.88 | QPCT (0.39) | CYP19A1HMOX1ALDH1A1QPCT | |
| SCHEMBL11269904 | 0.87 | HMOX1 (0.43) | HMOX1 | |
| SCHEMBL11259583 | 0.87 | HMOX1 (0.42) | CYP2A6CYP19A1CYP11B1CYP11B2CYP2B6 | |
| SCHEMBL11269136 | 0.86 | CYP2A6 (0.40) | CYP2A6CYP19A1CYP11B1CYP11B2CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4359475-A | SPERMICIDES, MICROBIOCIDES OR ANTICONVULSANTS | SYNTEX (U.S.A.) INC. (US) | 1982-11-16 | — | — | US | disclosed |