Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | GLS | O94925 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11256003 | 0.88 | MAPT (0.44) | MAPTNPC1GLSSMN1; SMN2RAB9A | |
| SCHEMBL11257125 | 0.80 | NPC1 (0.44) | MAPTNPC1GLSSMN1; SMN2RAB9A | |
| SCHEMBL11257042 | 0.77 | MAPT (0.41) | MAPTNPC1GLSSMN1; SMN2LMNA | |
| SCHEMBL11256038 | 0.76 | MAPT (0.41) | MAPTNPC1GLSSMN1; SMN2LMNA | |
| SCHEMBL11270826 | 0.75 | MAPT (0.39) | MAPTNPC1SMN1; SMN2RAB9ALMNA | |
| SCHEMBL11262084 | 0.74 | SMN1; SMN2 (0.57) | MAPTNPC1SMN1; SMN2RAB9ALMNA | |
| SCHEMBL11253904 | 0.72 | MAPT (0.49) | MAPTNPC1SMN1; SMN2RAB9ALMNA | |
| SCHEMBL11265038 | 0.71 | MAPT (0.41) | MAPTNPC1GLSSMN1; SMN2RAB9A | |
| SCHEMBL11259929 | 0.71 | MAPT (0.55) | MAPTNPC1GLSSMN1; SMN2RAB9A | |
| SCHEMBL2342623 | 0.69 | NPC1 (0.60) | MAPTNPC1GLSSMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344946-A | ANTIARTHRITICS, ANTIRHEUMATICS | BOEHRINGER INGELHEIM GMBH (DE) | 1982-08-17 | — | — | US | disclosed |