Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.57 |
| ▸ | LMNA | P02545 | 6/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.45 |
| ▸ | HPGD | P15428 | 7/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11259854 | 0.91 | SMN1; SMN2 (0.52) | SMN1; SMN2LMNANPSR1TSHRATM | |
| SCHEMBL11253904 | 0.83 | MAPT (0.49) | SMN1; SMN2LMNATSHRKDM4EALDH1A1 | |
| SCHEMBL11259222 | 0.79 | NPC1 (0.49) | SMN1; SMN2LMNATSHRALDH1A1HPGD | |
| SCHEMBL11262078 | 0.78 | ALDH1A1 (0.51) | SMN1; SMN2LMNANPSR1TSHRATM | |
| SCHEMBL11261115 | 0.75 | MAPT (0.51) | SMN1; SMN2LMNATSHRALDH1A1HPGD | |
| SCHEMBL11270839 | 0.74 | MAPT (0.45) | SMN1; SMN2LMNANPSR1TSHRKDM4E | |
| SCHEMBL11266789 | 0.72 | MAPT (0.46) | SMN1; SMN2LMNANPSR1TSHRKDM4E | |
| SCHEMBL11262589 | 0.72 | MAPT (0.48) | SMN1; SMN2LMNANPSR1TSHRALDH1A1 | |
| SCHEMBL11271738 | 0.72 | MAPT (0.48) | SMN1; SMN2LMNANPSR1TSHRALDH1A1 | |
| SCHEMBL11269297 | 0.71 | SMN1; SMN2 (0.47) | SMN1; SMN2LMNATSHRALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344946-A | ANTIARTHRITICS, ANTIRHEUMATICS | BOEHRINGER INGELHEIM GMBH (DE) | 1982-08-17 | — | — | US | disclosed |