SCHEMBL11270911

SCHEMBL11270911

C=CCc1c(Oc2ccc(C(=O)O)cc2)ccc(C(=O)O)c1CC=C

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.46
ALDH1A1 P00352 2/20 0.46
MAPT P10636 1/20 0.44
POLB P06746 2/20 0.42
APEX1 P27695 1/20 0.42
CTDSP1 Q9GZU7 1/20 0.42
PARP15 Q460N3 1/20 0.41
PARP10 Q53GL7 1/20 0.41
SRD5A2 P31213 2/20 0.41
HTT P42858 1/20 0.41
TTR P02766 2/20 0.40
PTGER4 P35408 2/20 0.40
PTGER2 P43116 1/20 0.40
PDE4B Q07343 1/20 0.40
PDE4D Q08499 1/20 0.40
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
RXRA P19793 1/20 0.37
PKM P14618 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL996835 0.79 CYP1A2 (0.44) L3MBTL1ALDH1A1PDE4BPDE4DCA1
SCHEMBL31208580 0.74 CYP3A4 (0.50) ALDH1A1MAPT
SCHEMBL8150648 0.73 PIM1 (0.41) L3MBTL1ALDH1A1PDE4BPDE4DRXRA
SCHEMBL11263451 0.73 APEX1 (0.44) L3MBTL1ALDH1A1MAPTPOLBAPEX1
SCHEMBL30435153 0.72 TTR (0.57) L3MBTL1ALDH1A1POLBAPEX1CTDSP1
SCHEMBL30497476 0.72 TTR (0.54) L3MBTL1ALDH1A1POLBAPEX1CTDSP1
SCHEMBL10693944 0.72 SRD5A1 (0.45) ALDH1A1MAPTPOLBHTTCA1
SCHEMBL1349070 0.72 GAA (0.39) ALDH1A1MAPTPOLBRXRA
SCHEMBL11337000 0.72 TTR (0.57) L3MBTL1ALDH1A1POLBAPEX1CTDSP1
SCHEMBL11322194 0.72 TTR (0.54) L3MBTL1ALDH1A1POLBAPEX1CTDSP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE31103-E HEAT RESISTANT DIELECTRIC FLUOROPOLYMERS RAYCHEM CORPORATION (US) 1982-12-14 US claimed
US-4121001-A IMIDE OR DIIMIDE RAYCHEM CORPORATION (US) 1978-10-17 US claimed
US-3970770-A Wire coated with fluorocarbon polymers cross-linked with dialyl ester of 4,4'-dicarboxydiphenyl ester INTERNATIONAL TELEPHONE AND TELEGRAPH CORPORATION (US) 1976-07-20 US disclosed