SCHEMBL11263451

SCHEMBL11263451

C=CCc1c(C(=O)O)ccc(S(=O)(=O)c2ccc(C(=O)O)cc2)c1CC=C

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APEX1 P27695 3/20 0.44
POLB P06746 3/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
KDM4E B2RXH2 2/20 0.44
CTDSP1 Q9GZU7 1/20 0.44
KMT2A Q03164 4/20 0.42
MEN1 O00255 3/20 0.42
CA12 O43570 3/20 0.39
CA1 P00915 3/20 0.39
CA2 P00918 3/20 0.39
CA9 Q16790 3/20 0.39
CA14 Q9ULX7 3/20 0.39
CA3 P07451 2/20 0.39
CA6 P23280 2/20 0.39
CA5A P35218 2/20 0.39
CA7 P43166 2/20 0.39
CA5B Q9Y2D0 2/20 0.39
CYP2C19 P33261 1/20 0.39
MAPT P10636 2/20 0.38
APOBEC3A P31941 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL996835 0.78 CYP1A2 (0.44) L3MBTL1KDM4EKMT2ACA12CA1
SCHEMBL4621555 0.76 ALDH1A1 (0.46) APEX1POLBL3MBTL1KDM4ECTDSP1
SCHEMBL11270911 0.73 L3MBTL1 (0.46) APEX1POLBL3MBTL1CTDSP1CA1
SCHEMBL5329793 0.72 KDM4E (0.35) KDM4ETDP1RXRAALDH1A1TSHR
SCHEMBL5059731 0.72 APEX1 (0.56) APEX1POLBL3MBTL1KDM4ECTDSP1
SCHEMBL8150648 0.72 PIM1 (0.41) L3MBTL1KDM4EKMT2AMEN1RXRA
SCHEMBL10425701 0.72 HSD17B13 (0.51) APEX1POLBL3MBTL1KDM4ECTDSP1
SCHEMBL7196091 0.71 APEX1 (0.48) APEX1POLBL3MBTL1KDM4ECTDSP1
SCHEMBL6287019 0.71 POLB (0.50) POLBCA12CA1CA2CA9
SCHEMBL10693944 0.71 SRD5A1 (0.45) POLBKDM4EKMT2AMEN1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE31103-E HEAT RESISTANT DIELECTRIC FLUOROPOLYMERS RAYCHEM CORPORATION (US) 1982-12-14 US claimed
US-4121001-A IMIDE OR DIIMIDE RAYCHEM CORPORATION (US) 1978-10-17 US claimed
US-RE31103-E HEAT RESISTANT DIELECTRIC FLUOROPOLYMERS RAYCHEM CORPORATION (US) 1982-12-14 US disclosed