Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | L3MBTL3 | Q96JM7 | 9/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 8/20 | 0.40 |
| ▸ | MBTD1 | Q05BQ5 | 6/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TP53BP1 | Q12888 | 3/20 | 0.39 |
| ▸ | L3MBTL4 | Q8NA19 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12226458 | 0.82 | KDM4E (0.51) | KDM4EALDH1A1L3MBTL3L3MBTL1MBTD1 | |
| SCHEMBL24331648 | 0.82 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL12640340 | 0.81 | KDM4E (0.54) | KDM4EALDH1A1L3MBTL3L3MBTL1MBTD1 | |
| SCHEMBL11269504 | 0.80 | ALDH1A1 (0.53) | ALDH1A1L3MBTL1SMN1; SMN2MAPTMAPK1 | |
| SCHEMBL11274698 | 0.79 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL28865573 | 0.78 | ALDH1A1 (0.46) | KDM4EALDH1A1L3MBTL3L3MBTL1MBTD1 | |
| SCHEMBL5173732 | 0.77 | KDM4E (0.56) | KDM4EALDH1A1L3MBTL3L3MBTL1MBTD1 | |
| Hydrochloric Acid SCHEMBL1373936 | 0.75 | KDM4E (0.55) | KDM4EALDH1A1L3MBTL3L3MBTL1MBTD1 | |
| SCHEMBL4041964 | 0.75 | KDM4E (0.59) | KDM4EALDH1A1L3MBTL3L3MBTL1MBTD1 | |
| SCHEMBL4472836 | 0.75 | KDM4E (0.51) | KDM4EALDH1A1L3MBTL3L3MBTL1MBTD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4316903-A | BACTERICIDES AND FUNGICIDES | MERCK & CO., INC. (US) | 1982-02-23 | — | — | US | disclosed |