Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 7/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PHGDH | O43175 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1126906 | 0.88 | GAA (0.35) | LMNAUSP2MAPTMAPK1ALDH1A1 | |
| SCHEMBL1987967 | 0.84 | MAPT (0.41) | LMNAUSP2MAPTMAPK1ALDH1A1 | |
| SCHEMBL1127435 | 0.78 | MAPT (0.40) | LMNAUSP2MAPTMAPK1HTT | |
| SCHEMBL1126647 | 0.77 | MAPT (0.40) | LMNAUSP2MAPTMAPK1ALDH1A1 | |
| SCHEMBL1126935 | 0.76 | GRIN2D (0.41) | LMNAUSP2MAPTMAPK1ALDH1A1 | |
| SCHEMBL1127284 | 0.76 | MAPT (0.42) | LMNAUSP2MAPTMAPK1HTT | |
| SCHEMBL30234731 | 0.76 | MAPT (0.42) | LMNAUSP2MAPTMAPK1HTT | |
| SCHEMBL1127230 | 0.76 | LMNA (0.40) | LMNAUSP2MAPTMAPK1HTT | |
| SCHEMBL1127162 | 0.76 | MAPT (0.41) | LMNAUSP2MAPTMAPK1HTT | |
| SCHEMBL1126481 | 0.76 | KCNA5 (0.41) | LMNAUSP2MAPTMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283006-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G Limited (GB) | 2011-02-16 | — | — | EP | claimed |
| WO-2009130481-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2009-10-29 | — | — | WO | claimed |