Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 8/20 | 0.45 |
| ▸ | MEN1 | O00255 | 7/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.45 |
| ▸ | MAOB | P27338 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.45 |
| ▸ | RELA | Q04206 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11263331 | 0.80 | ATM (0.41) | ALDH1A1CYP3A4KDM4ERAB9ANPC1 | |
| SCHEMBL22721784 | 0.75 | GSTP1 (0.70) | KDM4EMAPTMEN1KMT2ACYP2C9 | |
| SCHEMBL11281901 | 0.73 | NR4A2 (0.52) | ALDH1A1CYP3A4KDM4ERAB9ANPC1 | |
| SCHEMBL11264995 | 0.72 | ALDH1A1 (0.47) | ALDH1A1CYP3A4KDM4ERAB9ANPC1 | |
| SCHEMBL5623513 | 0.70 | CYP3A4 (0.69) | ALDH1A1CYP3A4KDM4ERAB9ANPC1 | |
| SCHEMBL4835218 | 0.70 | ADORA1 (0.51) | ALDH1A1CYP3A4KDM4ERAB9ANPC1 | |
| SCHEMBL11084829 | 0.69 | EGFR (0.71) | ALDH1A1CYP3A4KDM4ERAB9ANPC1 | |
| SCHEMBL11274526 | 0.69 | MAPT (0.49) | ALDH1A1CYP3A4KDM4ERAB9ANPC1 | |
| SCHEMBL11625458 | 0.69 | POLB (0.43) | ALDH1A1CYP3A4KDM4ERAB9ANPC1 | |
| SCHEMBL10967161 | 0.67 | ABL1 (0.67) | ALDH1A1CYP3A4KDM4ERAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4364956-A | ASTHMA | LILLY INDUSTRIES LIMITED (GB) | 1982-12-21 | — | — | US | disclosed |