Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.70 |
| ▸ | RAB9A | P51151 | 2/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.68 |
| ▸ | MAPT | P10636 | 4/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | TNF | P01375 | 1/20 | 0.53 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.53 |
| ▸ | KDR | P35968 | 4/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.51 |
| ▸ | TNNI3K | Q59H18 | 4/20 | 0.51 |
| ▸ | BRAF | P15056 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11271819 | 0.90 | GAA (0.67) | GAARAB9AL3MBTL1MAPTMAPK1 | |
| SCHEMBL11572993 | 0.85 | TP53 (0.77) | RAB9ATP53POLBKDRMAPK14 | |
| SCHEMBL11276153 | 0.85 | TP53 (0.68) | TP53KDRMAPK14TNNI3KBRAF | |
| SCHEMBL30002112 | 0.83 | GAA (0.78) | GAARAB9AL3MBTL1MAPTMAPK1 | |
| SCHEMBL10310308 | 0.81 | GAA (0.67) | GAARAB9AL3MBTL1MAPTMAPK1 | |
| SCHEMBL11404638 | 0.79 | GAA (0.68) | GAARAB9AL3MBTL1MAPTMAPK1 | |
| SCHEMBL6235785 | 0.78 | TP53 (0.62) | RAB9AMAPTKDM4ETP53NPC1 | |
| SCHEMBL11688772 | 0.78 | LIPE (0.51) | MAPTKDM4EMEN1KMT2A | |
| SCHEMBL11345354 | 0.78 | TP53 (0.62) | GAAL3MBTL1MAPTALDH1A1KDM4E | |
| SCHEMBL14784814 | 0.78 | GAA (0.74) | GAARAB9AL3MBTL1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4334912-A | HERBICIDES WHICH ARE NONPHYTOTOXIC TO CROPS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-06-15 | — | — | US | claimed |
| US-4334912-A | HERBICIDES WHICH ARE NONPHYTOTOXIC TO CROPS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-06-15 | — | — | US | disclosed |