Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.68 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.60 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.60 |
| ▸ | KDR | P35968 | 4/20 | 0.56 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.56 |
| ▸ | TNNI3K | Q59H18 | 3/20 | 0.56 |
| ▸ | BRAF | P15056 | 2/20 | 0.56 |
| ▸ | P2RY1 | P47900 | 3/20 | 0.53 |
| ▸ | PLK4 | O00444 | 1/20 | 0.52 |
| ▸ | AURKA | O14965 | 1/20 | 0.52 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.52 |
| ▸ | JAK2 | O60674 | 1/20 | 0.52 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.52 |
| ▸ | ABL1 | P00519 | 1/20 | 0.52 |
| ▸ | LCK | P06239 | 1/20 | 0.52 |
| ▸ | FYN | P06241 | 1/20 | 0.52 |
| ▸ | LYN | P07948 | 1/20 | 0.52 |
| ▸ | RET | P07949 | 1/20 | 0.52 |
| ▸ | ROS1 | P08922 | 1/20 | 0.52 |
| ▸ | SRC | P12931 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11572993 | 0.92 | TP53 (0.77) | TP53TLR8TLR7KDRMAPK14 | |
| SCHEMBL11273389 | 0.89 | TLR8 (0.56) | TP53TLR8TLR7KDRMAPK14 | |
| SCHEMBL11345354 | 0.88 | TP53 (0.62) | TP53KDRMAPK14TNNI3KBRAF | |
| SCHEMBL14384680 | 0.86 | MTNR1A (0.66) | TLR8TLR7KDRMAPK14TNNI3K | |
| SCHEMBL11582431 | 0.86 | TP53 (0.57) | TP53KDRMAPK14TNNI3KBRAF | |
| SCHEMBL11272027 | 0.85 | GAA (0.70) | TP53KDRMAPK14TNNI3KBRAF | |
| SCHEMBL11584161 | 0.85 | STK39 (0.64) | TP53TLR8TLR7KDRMAPK14 | |
| SCHEMBL11583889 | 0.84 | KDR (0.63) | TLR8TLR7KDRMAPK14TNNI3K | |
| SCHEMBL11581513 | 0.84 | KIF11 (0.64) | TLR8TLR7KDRMAPK14TNNI3K | |
| SCHEMBL11391977 | 0.83 | TLR8 (0.51) | TP53TLR8TLR7KDRMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4087272-A | POSTEMERGENCE HERBICIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1978-05-02 | — | — | US | claimed |
| US-4334912-A | HERBICIDES WHICH ARE NONPHYTOTOXIC TO CROPS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-06-15 | — | — | US | disclosed |